Tuberculosis

Patients with malignant lesions of the blood system is always considered as a group at risk of developing tuberculosis,

The purpose of the study was to examine the clinical symptoms of informativeness main methods of diagnosis and effectiveness of tuberculostatic treatment hemoblastoses in combination with TB.

Materials and methods. Analyzed 79 case histories of patients with a combination of acute tuberculosis with hematological malignancies brand name viagra from 1990 to 1999. among hospitalized in the Medical Sciences Research Center. 14 of them - patients with lymphosarcoma, 8 - lymphomas and limfotsitomoy, 27 - Hodgkin.

All patients used the histological and cytological methods for studying tissue samples from various organs and tissues, bacteriological, immunological (antibody detection of TB) research. In 59 patients studied bronchoalveolar fluid, sputum and blood by PCR (polymerase chain reaction) to detect DNA of Mycobacterium tuberculosis.

Results and discussion. The clinic patients with comorbidity dominated long feverish syndrome, which did not yield enhanced antibacterial, antifungal and antiviral therapy.

Active tuberculosis developed a mean of 2.6% - of patients with hematological malignancies, including 3% - of patients with LPZ (lymphoproliferative disease), 4% - in patients with Hodgkin. 2% - MPD (myeloproliferative disease) and 1% - AL (acute leukemia), which allows you to include this category of patients to a group of particularly high risk of joining a specific infection.

Difficulties in the diagnosis of tuberculosis that developed in patients with hematological malignancies, due to low informativeness of the most reliable methods of verification of this diagnosis. Positive results of bacteriological and histological methods of investigation were obtained in 28% of patients with different forms of hemoblastoses. The exception are the extrapulmonary localization of tuberculosis, in which the histological examination in 60% of the cases yielded positive results.

The complex clinical and radiological methods of investigation with a high suspicion for tuberculosis suspect allowed the development of this infection in 52% of hypertensive patients (64% with pulmonary localization), and confirm the accuracy of the diagnosis Viagra Is it possible Viagra will help you pronounced effect after the appointment of anti-TB therapy.

Conclusion. Difficulties in the diagnosis of tuberculosis that developed in patients with hematological malignancies, due to low informativeness of the most reliable methods of verification of the infection. Therefore, in addition to the targeted conduct a standard diagnosis of tuberculosis, bacteriological and histological - special attention should be paid to clinical methods of diagnosis, focusing on increased vigilance in respect of a substantial incidence of tuberculosis in these patients.

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